Below is a list of recent publications in which students of our DTP have been involved. The complete list can be found in the left panel of this page.
Guscott, M.A., McClelland, S.E. Experimental evolution of cancer chromosomal changes. Nat Genet (2024). https://doi.org/10.1038/s41588-024-01742-6
Graham LV, Fisher JG, Khakoo SI, Blunt MD. Targeting KIR as a novel approach to improve CAR-NK cell function. Journal of Translational Genetics and Genomics. 2023; 7(4): 230-5. http://dx.doi.org/10.20517/jtgg.2023.25
Andrade, J.R., Gallagher, A.D., Maharaj, J. et al. Disentangling the roles of aneuploidy, chromosomal instability and tumour heterogeneity in developing resistance to cancer therapies. Chromosome Res 31, 28 (2023). https://doi.org/10.1007/s10577-023-09737-5
Fisher, J.G., Doyle, A.D.P., Graham, L.V. et al. XPO1 inhibition sensitises CLL cells to NK cell mediated cytotoxicity and overcomes HLA-E expression. Leukemia 37, 2036–2049 (2023). https://doi.org/10.1038/s41375-023-01984-z
Lawrence, R., Watters, M., Davies, C.R. et al. Circulating tumour cells for early detection of clinically relevant cancer. Nat Rev Clin Oncol 20, 487–500 (2023). https://doi.org/10.1038/s41571-023-00781-y
Sirvent, S., Vallejo, A.F., Corden, E. et al. Impaired expression of metallothioneins contributes to allergen-induced inflammation in patients with atopic dermatitis. Nat Commun 14, 2880 (2023). https://doi.org/10.1038/s41467-023-38588-1
Relton, E.l., Roth, N.J., Yasa, S., Lefrancois, S., McCormick, P.J., Locker, N. et al. The Batten disease protein CLN3 is important for stress granules dynamics and translational activity. Journal of Biological Chemistry 299, 104649 (2023). https://doi.org/10.1016/j.jbc.2023.104649
Look A, Burns D, Tews I, Roghanian A and Mansour S (2023) Towards a better understanding of human iNKT cell subpopulations for improved clinical outcomes. Front. Immunol. 14:1176724. doi: 10.3389/fimmu.2023.1176724
Tovini, L., Johnson, S.C., Guscott, M.A. et al. Targeted assembly of ectopic kinetochores to induce chromosome‐specific segmental aneuploidies. The EMBO Journal 42: e11158 (2023). https://doi.org/10.15252/embj.2022111587
Monahan, K.J, Swinyard. O., Latchford, A. Biology of Precancers and Opportunities for Cancer Interception: Lesson from Colorectal Cancer Susceptibility Syndromes. Cancer Prev Res (Phila) 1 August 2023; 16 (8): 421–427. https://doi.org/10.1158/1940-6207.CAPR-22-0500
Higgins, L., Gerdes, H., Cutillas, P. R.; Principles of phosphoproteomics and applications in cancer research. Biochem J 29 March 2023; 480 (6): 403–420. doi: https://doi.org/10.1042/BCJ20220220
Tomas-Bort, E., Joseph, M.D., Wang, Q. et al. Purinergic GPCR-integrin interactions drive pancreatic cancer cell invasion. eLife 12:e86971 (2023) . https://doi.org/10.7554/eLife.86971
Gibson, S.V., Tomas Bort, E., Rodríguez-Fernández, L. et al. TGFβ-mediated MMP13 secretion drives myoepithelial cell dependent breast cancer progression. npj Breast Cancer 9, 9 (2023). https://doi.org/10.1038/s41523-023-00513-6
Clayton, K., Holbrook, D. J., Vallejo, A. et al. Skin programming of inflammatory responses to Staphylococcus aureus is compartmentalized according to epidermal keratinocyte differentiation status, British Journal of Dermatology, Volume 188, Issue 3, March 2023, Pages 396–406, https://doi.org/10.1093/bjd/ljac088
Davies CR, Guo T, Burke E, Stankiewicz E et al. The potential of using circulating tumour cells and their gene expression to predict docetaxel response in metastatic prostate cancer. Front. Oncol. 12:1060864 (2023). doi: 10.3389/fonc.2022.1060864
Fisher, J.G.; Doyle, A.D.P.; Graham, L.V.; Khakoo, S.I.; Blunt, M.D. Disruption of the NKG2A:HLA-E Immune Checkpoint Axis to Enhance NK Cell Activation against Cancer. Vaccines (2022), 10, 1993. https://doi.org/10.3390/vaccines10121993
Akoto, C.; Willis, A.; Banas, C.F.; Bell, J.A.; Bryant, D.; Blume, C.; Davies, D.E.; Swindle, E.J. IL-33 Induces an Antiviral Signature in Mast Cells but Enhances Their Permissiveness for Human Rhinovirus Infection. Viruses (2022), 14, 2430. https://doi.org/10.3390/v14112430
Forfar, R., Hussain, M., Khurana, P., Cook, J., Lewis, S., Popat, D., et al. Identification of a novel specific small-molecule melanocortin-2-receptor antagonist. Endocrine Connections, 11(12), e220338 (2022). https://doi.org/10.1530/EC-22-0338