Below is a list of recent publications in which students of our DTP have been involved. The complete list can be found in the left panel of this page.
Valero-Hernandez E, Mathur J, Baker D, et al. Lymphocytosis as a biomarker for natalizumab treatment response in multiple sclerosis: The link with anti-drug antibodies. Multiple Sclerosis Journal. 2026;0(0). doi:10.1177/13524585261495351
Harding, D. T., Graham, L. V., Bartlett, L. G., et al.. (2026). Selinexor potentiates NK cell activation against multiple myeloma. Clinical and experimental immunology, 220(1), uxag059. https://doi.org/10.1093/cei/uxag059
M. Milton, S. H. Farag, D. Garay-Baquero, J. Gullick, K. Niedobecka,et al. (2026). Human CD1c-autoreactive T-cells recognise Mycobacterium tuberculosis–infected antigen-presenting cells and display cytotoxic effector programmes eLife 15:RP110341 https://doi.org/10.7554/eLife.110341.2
Giovannoni, G. Payne, O., Valero-Hernández, E.., et al., Post-streptococcal Autoimmunity and Its Relevance to Epstein–Barr virus as the Potential Cause of Multiple Sclerosis, The Journal of Infectious Diseases, Volume 234, Issue 1, 15 July 2026, Pages 6–8, https://doi.org/10.1093/infdis/jiag035
Parker, H., Mirandari, A., Stevens, B., et al.. (2026). Integrated multiomic profiling reveals 2 distinct splenic marginal zone lymphoma subgroups with prognostic relevance. Blood advances, 10(14), 4943–4957. https://doi.org/10.1182/bloodadvances.2025019336
Mårtensson, L., Holmkvist, P., Cleary, K. L., et al.. (2026). Ligand-Blocking and Agonist Antibodies Targeting TNFR2 Employ Distinct Modes of Action to Induce Antitumor Immunity. Cancer research, 86(20), 5109–5129. https://doi.org/10.1158/0008-5472.CAN-26-0274
Natasha H.C. Easton, Lareb S.N. Dean, et al. Ultrafine particulate matter emitted from ships drives inflammation and susceptibility to viral infection, Environment International, Volume 214, 2026, 110381, https://doi.org/10.1016/j.envint.2026.110381.
Tarantola, L., Tyler, E.J., Liu, Y. et al. Glycosylated extracellular matrix drives immune suppression by modulating macrophage-T cell crosstalk in triple-negative breast cancer. Nat Commun 17, 5008 (2026). https://doi.org/10.1038/s41467-026-73467-5
Ermogenous, C., Brucoli, M. Perini, A., …, Beattie, G., Kafka, A. Ombrato, L. (2026). MIF mediates monocyte-dependent inhibition of natural killer cell cytotoxicity in triple-negative breast cancer. Cell Reports (45), https://doi.org/10.1016/j.celrep.2026.117431
Bloom, BM, Payne, O., Valero-Hernandez, E., et al. Multiple sclerosis and autoimmunity: learnings from post-streptococcal autoimmunity. Multiple Sclerosis and Related Disorders 109, 107091 (May 2026). https://doi.org/10.1016/j.msard.2026.107091
Dontamsetti, K. D., Aktar, R., & Peiris, M. (2026). Systematic Characterisation of GLP-1R in Human Enteric Nervous System: Implications for GLP-1 as a Key Regulator of Colonic Activity. Journal of neurochemistry, 170(5), e70461. https://doi.org/10.1111/jnc.70461
Panagi, M., Mpekris, F., Burger Ramos, M., Voutouri, C., Michael, C., Pearce, O. M. T., Correa de Sampaio, P., Soulier, A., & Stylianopoulos, T. (2026). Synthetic inducible bacteria normalize the microenvironment of refractory tumors, potentiating checkpoint inhibitor responses. Molecular cancer therapeutics, 10.1158/1535-7163.MCT-25-0203. Advance online publication. https://doi.org/10.1158/1535-7163.MCT-25-0203
Morelli, T., Geeves, M. E., Mohammed, A., et al. (2026). Beyond spirometry: understanding COPD origins to support a new diagnostic approach. ERJ open research, 12(2), 00885-2025. https://doi.org/10.1183/23120541.00885-2025
Parker, H., Carr, L., Norris, K., Nilsson-Takeuchi, A., Stevens, B., Amarasinghe, H., Kadalayil, L., Else, M., Clifford, R., Pettitt, A., Munir, T., Schuh, A., Walewska, R., Baird, D. M., Oscier, D. G., Pepper, C., Bryant, D., Gibson, J., & Strefford, J. C. (2026). High-risk molecular features may eclipse genomic complexity in predicting chronic lymphocytic leukemia outcomes; UK clinical trial insights. Leukemia, 10.1038/s41375-026-02906-5. https://doi.org/10.1038/s41375-026-02906-5
Abdolkarimi, D., Liu, Y., Gilchrist, L. et al. Circulating inflammatory proteins predict dementia risk, and are linked to structural brain changes and modifiable risk factors. Alz Res Therapy 18, 27 (2026). https://doi.org/10.1186/s13195-025-01951-z
Deenonpoe, R., Guscott, M.A., Watcharadetwittaya, S., McNeill, I.L., Moralli, D., Shaikh, N. and McClelland, S.E. Chromosomal instability and genomic alterations in cholangiocarcinoma from Northeastern Thailand. J. Pathol, 2025 Nov;267(3):261-274. https://doi.org/10.1002/path.6464
Sofia, C, Parkin, JGH, Bell, JA, et al. Air pollution and alveolar health. European Respiratory Review, 2025 34(177): 240280; DOI: https://doi.org/10.1183/16000617.0280-2024.
Palmer N , Khakoo S , Sanchez-Elsner T , Vallejo AF. Enhancing natural killer cell anti-tumour activity through macrophage manipulation. Frontiers in Immunology, 2025 (16): 1664-3224. doi: 10.3389/fimmu.2025.1656925
Graziani, Vittoria et al. SLC7A11 protects amoeboid-disseminating cancer cells from oxidative stress. Cell Reports, Volume 44, Issue 7, 115939. DOI: 10.1016/j.celrep.2025.115939
Milton M, Mansour S. CD1-restricted T cells: are unconventional allies the key to future TB vaccines? Frontiers in Immunology, 2025 Jul 10;16:1629466. doi: 10.3389/fimmu.2025.1629466.
Ogden S, Metic N, Leylek O, Smith EA, et al. Phenotypic heterogeneity and plasticity in colorectal cancer metastasis. Cell Genomics,
2025. https://doi.org/10.1016/j.xgen.2025.100881.
Tarcan A, et al., In-vitro analysis of cellular bioenergetics reveal a reduced mitochondrial spare respiratory capacity in bronchial epithelial cells of COPD patients. ERJ Open Research 2025 11(suppl 15): TP209; DOI: https://doi.org/10.1183/23120541.LSC-2025.TP209
Zhao Z, Cutmore LC, Baleeiro RB, Hartlebury JJ, Brown N, Chard-Dunmall L, Lemoine N, Wang Y, Marshall JF. The Combination of Oncolytic Virus and Antibody Blockade of TGF-β Enhances the Efficacy of αvβ6-Targeting CAR T Cells Against Pancreatic Cancer in an Immunocompetent Model. Cancers. 2025; 17(9):1534. https://doi.org/10.3390/cancers17091534
Hilary A. Kenny, Carman Ka Man Ip, Lucy Kelliher, et. al.; Navitoclax, a Bcl-2/xL Inhibitor, and YM155, a Survivin Inhibitor, in Combination with Carboplatin, Effectively Inhibit Ovarian Cancer Tumor Growth. Mol Cancer Ther 2025; https://doi.org/10.1158/1535-7163.MCT-23-0863
Rodriguez-Algarra T, Whittaker E, del Castillo del Rio S, K. Rakyan V. Assessing Human Ribosomal DNA Variation and Its Association With Phenotypic Outcomes. BioEssays 2025 Apr;47(4):e202400232. doi: 10.1002/bies.202400232.
Alves Martins R, Tekin MM, Cragg MS, Roghanian A. Therapeutic targeting of tumour-associated macrophage receptors, Immunotherapy Advances, 2025; ltaf009, https://doi.org/10.1093/immadv/ltaf009
Dawson, L.E., Sekar, A., Fulford, A.D. et al. The deubiquitylating enzyme Fat facets promotes Fat signalling and restricts tissue growth. Nat Commun 16, 1938 (2025). https://doi.org/10.1038/s41467-025-57164-3
Parkin, JGH, Dean, LSN, Bell, JA et al. Copper-enriched automotive brake wear particles perturb human alveolar cellular homeostasis. Part Fibre Toxicol 22, 4 (2025). https://doi.org/10.1186/s12989-024-00617-2
Savy T, Flanders L, Karpanasamy T et al.. Cancer evolution: from Darwin to the Extended Evolutionary Synthesis. Trends in Cancer. 2025; https://doi.org/10.1016/j.trecan.2025.01.001
Valero-Hernandez E, Tremoleda JL, Michael-Titus AT. Omega-3 Fatty Acids and Traumatic Injury in the Adult and Immature Brain. Nutrients. 2024; 16(23):4175. https://doi.org/10.3390/nu16234175
Ermogenous C, Ombrato L, Beattie G. Abstract B022: Investigating how monocytes impair NK cell cytotoxicity in lung metastasis of triple-negative breast cancer. Cancer Res 15 November 2024; 84 (22_Supplement): B022. https://doi.org/10.1158/1538-7445.TUMBODY-B022
Tarantola L, Keklikoglou I, Pearce OM. Abstract C045: The extracellular matrix glycoprotein periostin supports chemotherapy resistance by modulating macrophage recruitment and phagocytosis in triple negative breast cancer. Cancer Res 15 November 2024; 84 (22_Supplement): C045. https://doi.org/10.1158/1538-7445.TUMBODY-C045
Sofia C, Edgeway L, Parkin J et al. The effect of air pollution on the antiviral immune response in pulmonary fibrosis. European Respiratory Journal 2024 64(suppl 68): PA4453; DOI: https://doi.org/10.1183/13993003.congress-2024.PA4453
O’Sullivan, E.A., Wallis, R., Mossa, F. et al. The paradox of senescent-marker positive cancer cells: challenges and opportunities. npj Aging 10, 41 (2024). https://doi.org/10.1038/s41514-024-00168-y
Carr, L., Norris, K., Parker, H., Nilsson-Takeuchi, A. et al. Telomere length and DNA methylation epitype both provide independent prognostic information in CLL patients; data from the UK CLL4, ARCTIC and ADMIRE clinical trials. Br J Haematol (2024). https://doi.org/10.1111/bjh.19765
Graham LV, Fisher JG, Doyle ADP, Sale B, Del Rio L, French AJE, Mayor NP, Turner TR, Marsh SGE, Cragg MS, Forconi F, Khakoo SI and Blunt MD. KIR2DS2+ NK cells in cancer patients demonstrate high activation in response to tumour-targeting antibodies. Front. Oncol. (2024). 14:1404051. doi: 10.3389/fonc.2024.1404051
Bell, J.A., Davies, E.R., Brereton, C.J., et al. Spatial transcriptomic validation of a biomimetic model of fibrosis enables re-evaluation of a therapeutic antibody targeting LOXL2, Cell Reports Medicine 5, 9 (2024). https://doi.org/10.1016/j.xcrm.2024.101695
Hill BR, Ozgencil M, Buckley-Benbow L, Skingsley SLP, Tomlinson D, Eizmendi CO, Agnarelli A, Bellelli R. Loss of POLE3-POLE4 unleashes replicative gap accumulation upon treatment with PARP inhibitors. Cell Rep. 2024 May 28;43(5):114205. doi: 10.1016/j.celrep.2024.114205.
Dontamsetti KD, Pedrosa-Suarez LC, Aktar R, Peiris M. Sensing of luminal contents and downstream modulation of GI function. JGH Open. 2024 May 22;8(5):e13083. doi: 10.1002/jgh3.13083.
Guscott, M.A., McClelland, S.E. Experimental evolution of cancer chromosomal changes. Nat Genet (2024). https://doi.org/10.1038/s41588-024-01742-6
Kafka A, Ermogenous C, Ombrato L (2024). Isolation of Live Immune Cells from the Tumor Microenvironment by FACS. In: Siciliano, V., Ceroni, F. (eds) Cancer Immunotherapy. Methods in Molecular Biology, vol 2748. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-3593-3_1
Elhassan YS, Appenzeller S., Landwehr LS, Lippert J, Popat D et al. Primary unilateral macronodular adrenal hyperplasia with concomitant glucocorticoid and androgen excess and KDM1A inactivation, European Journal of Endocrinology, Volume 191, Issue 3, September 2024, Pages 334–344, https://doi.org/10.1093/ejendo/lvae106
Ramakrishnan A, Popat D, Purushothaman P, Chan LF, Gevers EF. A Novel Maternally Inherited GNAS Variant in a Family With Hyperphagia and Obesity: 3 Cases, JCEM Case Reports, Volume 2, Issue 8, August 2024, luae125, https://doi.org/10.1210/jcemcr/luae125