Southampton
Research Theme | PhD Project Title | PhD Supervisor | Faculty/School | Cohort Start Date | Funding |
---|---|---|---|---|---|
Reproductive Cell Biology | Can endometrial gland structure and function help us understand why some women are more at risk of miscarriage than others? | Jane Cleal | Medicine/Human Development and Health | 2023 | WMR/Rosetrees |
Stem Cell Biology | Uncovering the drivers of non-alcoholic fatty liver disease progression using patient derived organoids | Nicole Prior | Medicine/Human Development and Health | 2023 | BSR |
Neurodegenerative Diseases | Investigating the function of SLC15A3: a promising gene linked to Alzheimer’s disease | Diego Gomez-Nicola | Medicine/Clinical and Experimental Sciences | 2023 | MRC-DTP |
Neurological Diseases | New chemical approaches to improve A-to-I RNA editing with the aim of restoring sight loss associated with oculocutaneous albinism (OCA) | Ysobel Baker | Medicine/Clinical and Experimental Sciences | 2023 | MRC-DTP/IfLS |
Neurodegenerative Diseases | Studying the role of environmental factors on microglia in Alzheimer’s Disease using human brain organoids. | Diego Gomez-Nicola | Medicine/Clinical and Experimental Sciences | 2023 | MRC-DTP |
Cancer | Investigating the role of NK-innate immune cell interactions in oesophageal cancer. | Matthew Blunt | Medicine/Cancer Sciences | 2023 | MRC-DTP |
Cancer | Investigating the genomic structure, regulation and function of the low affinity FCGR cluster to improve cancer immunotherapy. | Jane Gibson | Medicine/Cancer Sciences | 2023 | WMR/CITF |
Cancer | Investigating the association between Crown Like Structures and body composition parameters on the tumour-immune microenvironment in high risk breast cancer. | Constantinos Savva | Medicine/Cancer Sciences | 2023 | CRUK/CITF |
Cancer | Identification and validation of novel therapeutic targets for the treatment of esophageal adenocarcinoma | Dean Bryant | Medicine/Cancer Sciences | 2023 | University of Southampton |
Cancer | Investigation into the role of NKG2A in CAR-T and CAR-NK cell activation against lymphoma | Matthew Blunt | Medicine/Cancer Sciences | 2023 | CRUK/CITF |
Cancer Immunology | The effect of existing immune memory on CD8+ T cell responses to in situ cancer vaccines | Edd James | Medicine/Cancer Sciences | 2023 | CRUK/CITF |
Cancer Immunology | Investigating the structure:function relationships of a novel human myeloid checkpoint receptor (LILRB3) and its specific immunomodulating monoclonal antibodies | Ali Roghanian | Medicine/Cancer Sciences | 2023 | MRC iCASE |
Immunity & Infection | Determining the modes of action and application for antimicrobial mix metal complexes in the presence of biofilms. | Sandra Wilks | Environmental and Life Sciences/Biology | 2024 | MRC iCASE |
Cancer | Therapeutic targeting of hypoxia inducible factors to augment anti-cancer antibody immunotherapy | Mark Cragg | Medicine/Cancer Sciences | 2024 | MRC iCASE |
Immunity & Infection | Next generation light controlled antimicrobials with “on-off” activity for the treatment of wound infections | Matthias Baud | Engineering and Physical Sciences/Chemistry | 2024 | MRC iCASE |
Immunity & Infection | A multi-disciplinary study into air pollution-associated transition metal homeostasis in the lungs | Matt Loxham | Medicine/Clinical and Experimental Sciences | 2022 | MRC-DTP |
Immunity & Infection | Mis-programming of mesenchymal cells in human lung fibrosis | Mark Jones | Medicine/Clinical and Experimental Sciences | 2022 | MRC-DTP |
Immunity & Infection | Exploring the function of exosomes in Mycobacterium tuberculosis host-pathogen interaction, and their effect on infection outcome | Liku Tezera | Medicine/Clinical and Experimental Sciences | 2022 | MRC-DTP |
Regenerative Medicine | Developing an antimicrobial release strategy using nanoclay gels to treat osteomyelitis | Jon Dawson | Medicine/Human Development and Health | 2022 | MRC iCASE |
Cancer | A data-driven approach to controlling immune cell states for the optimisation of novel anti-cancer immunotherapeutic approaches | Owen Rackham | Medicine/Cancer Sciences | 2022 | MRC-DTP |
Cancer | APOBEC3A-mediated RNA editing as a source of cancer antigens: A proof-of-concept study | Tim Fenton | Medicine/Cancer Sciences | 2022 | Oddfellows |
Cancer | Deciphering the role of GABAergic signalling in tumour vascularization | Yury Bogdanov | Medicine/Cancer Sciences | 2022 | WMR/CITF |
Cancer | Understanding and improving the mechanisms of action of antiGD2 chemo-immunotherapy in Neuroblastoma | Juliet Gray | Medicine/Cancer Sciences | 2022 | WMR/CITF |
Immunity & Infection | Investigating mitochondrial dysfunction as a driver of COPD | Karl Staples | Medicine/Clinical and Experimental Sciences | 2022 | MRC iCASE |
Immunity & Infection | Investigating the Role of Antisense RNA in the CCL3/CCR5/RALY Pathway | Elena Vorobeva | Medicine/Clinical and Experimental Sciences | 2021 | MRC-DTP |
Immunity & Infection | Investigating the interaction between macrophages and natural killer cells in the tumour microenvironment. | Salim Khakoo | Medicine/Clinical and Experimental Sciences | 2021 | MRC-DTP |
Cancer Immunology | Cancer Immunotherapy by Targeting 4-1BB with Novel Immunostimulatory Bispecific Antibodies | Aymen Al-Shamkhani | Medicine/Cancer Sciences | 2021 | MRC-DTP |
Cancer | Investigating the Effects of Obesity and Therapeutic Intervention on Immune Responses in Breast Cancer | Charles Birts | Medicine/Cancer Sciences | 2021 | MRC-DTP |
Cancer | Targeting NK cell regulatory receptors for the treatment of cancer | Matthew Blunt | Medicine/Cancer Sciences | 2021 | CITF |
Cancer Immunology | Evaluation of the Efficacy and Safety of LILRB3-Targeted Immunotherapies in Preclinical Models of Human AML | Ali Roghanian | Medicine/Cancer Sciences | 2021 | MRC iCASE |
Immunity & Infection | Investigating a role for activity-regulated cytoskeleton-associated protein in the mast cell response to external stimuli, including hydrogen peroxide exposure and Rhinovirus infection | Emily Swindle | Medicine/Clinical and Experimental Sciences | 2020 | MRC-DTP |
Immunity & Infection | Investigating the functional role of CD1 expression and defining protective and pathogenic CD1c-immunity in tuberculosis. | Salah Mansour | Medicine/Clinical and Experimental Sciences | 2020 | MRC-DTP |
Immunity & Infection | Precision Targeting of human iNKT Cells for Cancer Immunotherapy | Salah Mansour | Medicine/Clinical and Experimental Sciences | 2020 | MRC-DTP |
Cancer | Determining the role of activating and inhibitory signalling motifs present in T-cell expressed CD96 | Aymen Al-Shamkhani | Medicine/Cancer Sciences | 2020 | WMR/CITF |
Cancer | Investigating the role of human STING activation in myeloid cells for anti-tumour immunity | Stephen Beers | Medicine/Cancer Sciences | 2020 | CITF |
Cancer | The significance of oligomannose-type glycans on the surface immunoglobulin of lymphomas | Francesco Forconi | Medicine/Cancer Sciences | 2020 | Eyles |
Cancer | A Multi-Omics Approach to Explore the Genomic Landscape of Splenic Marginal Zone Lymphoma (SMZL) | Jon Strefford | Medicine/Cancer Sciences | 2020 | CITF |