Below is a list of recent publications in which students of our DTP have been involved. The complete list can be found in the left panel of this page.
Valero-Hernandez E, Tremoleda JL, Michael-Titus AT. Omega-3 Fatty Acids and Traumatic Injury in the Adult and Immature Brain. Nutrients. 2024; 16(23):4175. https://doi.org/10.3390/nu16234175
Ermogenous C, Ombrato L, Beattie G. Abstract B022: Investigating how monocytes impair NK cell cytotoxicity in lung metastasis of triple-negative breast cancer. Cancer Res 15 November 2024; 84 (22_Supplement): B022. https://doi.org/10.1158/1538-7445.TUMBODY-B022
Tarantola L, Keklikoglou I, Pearce OM. Abstract C045: The extracellular matrix glycoprotein periostin supports chemotherapy resistance by modulating macrophage recruitment and phagocytosis in triple negative breast cancer. Cancer Res 15 November 2024; 84 (22_Supplement): C045. https://doi.org/10.1158/1538-7445.TUMBODY-C045
Sofia C, Edgeway L, Parkin J et al. The effect of air pollution on the antiviral immune response in pulmonary fibrosis. European Respiratory Journal 2024 64(suppl 68): PA4453; DOI: https://doi.org/10.1183/13993003.congress-2024.PA4453
O’Sullivan, E.A., Wallis, R., Mossa, F. et al. The paradox of senescent-marker positive cancer cells: challenges and opportunities. npj Aging 10, 41 (2024). https://doi.org/10.1038/s41514-024-00168-y
Carr, L., Norris, K., Parker, H., Nilsson-Takeuchi, A. et al. Telomere length and DNA methylation epitype both provide independent prognostic information in CLL patients; data from the UK CLL4, ARCTIC and ADMIRE clinical trials. Br J Haematol (2024). https://doi.org/10.1111/bjh.19765
Graham LV, Fisher JG, Doyle ADP, Sale B, Del Rio L, French AJE, Mayor NP, Turner TR, Marsh SGE, Cragg MS, Forconi F, Khakoo SI and Blunt MD. KIR2DS2+ NK cells in cancer patients demonstrate high activation in response to tumour-targeting antibodies. Front. Oncol. (2024). 14:1404051. doi: 10.3389/fonc.2024.1404051
Bell, J.A., Davies, E.R., Brereton, C.J., et al. Spatial transcriptomic validation of a biomimetic model of fibrosis enables re-evaluation of a therapeutic antibody targeting LOXL2, Cell Reports Medicine 5, 9 (2024). https://doi.org/10.1016/j.xcrm.2024.101695
Hill BR, Ozgencil M, Buckley-Benbow L, Skingsley SLP, Tomlinson D, Eizmendi CO, Agnarelli A, Bellelli R. Loss of POLE3-POLE4 unleashes replicative gap accumulation upon treatment with PARP inhibitors. Cell Rep. 2024 May 28;43(5):114205. doi: 10.1016/j.celrep.2024.114205.
Dontamsetti KD, Pedrosa-Suarez LC, Aktar R, Peiris M. Sensing of luminal contents and downstream modulation of GI function. JGH Open. 2024 May 22;8(5):e13083. doi: 10.1002/jgh3.13083.
Guscott, M.A., McClelland, S.E. Experimental evolution of cancer chromosomal changes. Nat Genet (2024). https://doi.org/10.1038/s41588-024-01742-6
Kafka A, Ermogenous C, Ombrato L (2024). Isolation of Live Immune Cells from the Tumor Microenvironment by FACS. In: Siciliano, V., Ceroni, F. (eds) Cancer Immunotherapy. Methods in Molecular Biology, vol 2748. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-3593-3_1
Graham LV, Fisher JG, Khakoo SI, Blunt MD. Targeting KIR as a novel approach to improve CAR-NK cell function. Journal of Translational Genetics and Genomics. 2023; 7(4): 230-5. http://dx.doi.org/10.20517/jtgg.2023.25
Andrade, J.R., Gallagher, A.D., Maharaj, J. et al. Disentangling the roles of aneuploidy, chromosomal instability and tumour heterogeneity in developing resistance to cancer therapies. Chromosome Res 31, 28 (2023). https://doi.org/10.1007/s10577-023-09737-5
Elhassan YS, Appenzeller S., Landwehr LS, Lippert J, Popat D et al. Primary unilateral macronodular adrenal hyperplasia with concomitant glucocorticoid and androgen excess and KDM1A inactivation, European Journal of Endocrinology, Volume 191, Issue 3, September 2024, Pages 334–344, https://doi.org/10.1093/ejendo/lvae106
Ramakrishnan A, Popat D, Purushothaman P, Chan LF, Gevers EF. A Novel Maternally Inherited GNAS Variant in a Family With Hyperphagia and Obesity: 3 Cases, JCEM Case Reports, Volume 2, Issue 8, August 2024, luae125, https://doi.org/10.1210/jcemcr/luae125
Fisher, J.G., Doyle, A.D.P., Graham, L.V. et al. XPO1 inhibition sensitises CLL cells to NK cell mediated cytotoxicity and overcomes HLA-E expression. Leukemia 37, 2036–2049 (2023). https://doi.org/10.1038/s41375-023-01984-z
Lawrence, R., Watters, M., Davies, C.R. et al. Circulating tumour cells for early detection of clinically relevant cancer. Nat Rev Clin Oncol 20, 487–500 (2023). https://doi.org/10.1038/s41571-023-00781-y
Sirvent, S., Vallejo, A.F., Corden, E. et al. Impaired expression of metallothioneins contributes to allergen-induced inflammation in patients with atopic dermatitis. Nat Commun 14, 2880 (2023). https://doi.org/10.1038/s41467-023-38588-1
Relton, E.l., Roth, N.J., Yasa, S., Lefrancois, S., McCormick, P.J., Locker, N. et al. The Batten disease protein CLN3 is important for stress granules dynamics and translational activity. Journal of Biological Chemistry 299, 104649 (2023). https://doi.org/10.1016/j.jbc.2023.104649
Look A, Burns D, Tews I, Roghanian A and Mansour S (2023) Towards a better understanding of human iNKT cell subpopulations for improved clinical outcomes. Front. Immunol. 14:1176724. doi: 10.3389/fimmu.2023.1176724
Tovini, L., Johnson, S.C., Guscott, M.A. et al. Targeted assembly of ectopic kinetochores to induce chromosome‐specific segmental aneuploidies. The EMBO Journal 42: e11158 (2023). https://doi.org/10.15252/embj.2022111587
Monahan, K.J, Swinyard. O., Latchford, A. Biology of Precancers and Opportunities for Cancer Interception: Lesson from Colorectal Cancer Susceptibility Syndromes. Cancer Prev Res (Phila) 1 August 2023; 16 (8): 421–427. https://doi.org/10.1158/1940-6207.CAPR-22-0500
Higgins, L., Gerdes, H., Cutillas, P. R.; Principles of phosphoproteomics and applications in cancer research. Biochem J 29 March 2023; 480 (6): 403–420. doi: https://doi.org/10.1042/BCJ20220220
Tomas-Bort, E., Joseph, M.D., Wang, Q. et al. Purinergic GPCR-integrin interactions drive pancreatic cancer cell invasion. eLife 12:e86971 (2023) . https://doi.org/10.7554/eLife.86971
Gibson, S.V., Tomas Bort, E., Rodríguez-Fernández, L. et al. TGFβ-mediated MMP13 secretion drives myoepithelial cell dependent breast cancer progression. npj Breast Cancer 9, 9 (2023). https://doi.org/10.1038/s41523-023-00513-6
Clayton, K., Holbrook, D. J., Vallejo, A. et al. Skin programming of inflammatory responses to Staphylococcus aureus is compartmentalized according to epidermal keratinocyte differentiation status, British Journal of Dermatology, Volume 188, Issue 3, March 2023, Pages 396–406, https://doi.org/10.1093/bjd/ljac088
Davies CR, Guo T, Burke E, Stankiewicz E et al. The potential of using circulating tumour cells and their gene expression to predict docetaxel response in metastatic prostate cancer. Front. Oncol. 12:1060864 (2023). doi: 10.3389/fonc.2022.1060864